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MK-677 | Ibutamoren — NeoColloid® (SARM Matrix)

69.89
54.89
  USD

MK-677 is a drug that mimics growth hormone [§2 - T.O.U.] by binding to and activating the ghrelin receptor (i.e, ghrelin receptor agonist). This particular compound has been ostensibly called the "holy grail of aging research." [§2 - T.O.U.]

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What is MK-677?

MK-677 is a drug that mimics growth hormone [§2] by binding to and activating the ghrelin receptor (i.e, ghrelin receptor agonist). This particular compound has been ostensibly called the "holy grail of aging research" [§2]. MK-677 has been shown to stimulate GH release [§2] in vitro (EC50 = 1.3 nM) as well as increase plasma levels of GH [§2] when administered into rats' bodies, though it can be more difficult for this compound—due its high affinity with the ghrelin receptor—to penetrate cells at high doses than other compounds without such an affinity would have difficulty doing so.


•  Reduce Recovery Time
•  Increase Growth Hormone (GH) Levels

•  Increase IGF-1 Levels
•  Increase Muscle Tissue
•  Best Utilized in 12-24 Week Period

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Sarmmies™ is located in California and provides Free Standard Shipping within the United States (excls. may apply). Every order dispatched is tracked and insured (up to $499). Shipping rates to Canada and the rest of the world (limited) are calculated in your cart at the time of checkout and depend on package weight and the shipping method (and subsequent carrier) chosen.

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Our products may NOT be returned for fiat currency or store credit, barring extenuating circumstances + SARMMIES ANALYTICAL'S approval, and then, only in compliance with our return shipment instructions. This policy (and its rigid nature) is due to research compounds' intrinsic, non-returnable characteristics (e.g., contamination, safety, etc.).

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C27H36N4O5S

2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4';-piperidine]-1';-yl)-1-oxo-3-phenylmethoxypropan-2-yl]propanamide



"[... In the] short term, oral administration of MK-677 reverses the protein catabolism caused by dietary caloric restriction. These data suggest that MK-677 may be useful as adjunctive therapy in certain catabolic states. The degree of GH stimulation observed appears to be sufficient to improve nitrogen balance under the stress of caloric restriction." PubChem [NCBI]

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